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 Tuesday March 09, 2010       10:24 pm
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Pendrin is a novel autoantigen recognized by patients with autoimmune thyroid diseases.


Conclusions: The study identifies pendrin as a novel autoantigen recognized by patients with autoimmune thyroid diseases, and proposes the use of pendrin antibodies as an accurate diagnostic tool.
PMID: 19050049 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) MedWorm Message: Find out how you can get your message across here by sponsoring this MedWorm news feed.

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Pendrin is an apical protein of thyroid follicular cells, responsible for the efflux of iodide into the follicular lumen via an iodide-chloride transport mechanism. It is unknown whether pendrin is recognized by autoantibodies.

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