Granulomatous and lymphocytic thyroiditis associated with a follicular adenoma

Abstract  A 44-year-old woman came to medical attention with right thyroid lobe enlargement and weight loss. Thyroid scan and ultrasound
demonstrated a nodule in the right thyroid lobe; a right hemithyroidectomy was performed. Histologic examination documented
granulomatous and lymphocytic thyroiditis associated with a follicular adenoma. No inflammation was apparent within the adenoma.
The parallels between granulomatous thyroiditis and lymphocytic thyroiditis, including presumed viral initiation and deranged
immunologic function, suggest that granulomatous thyroiditis may evolve into chronic lymphocytic thyroiditis; this case may
be an example of such a transition. It is proposed that thyroid follicular adenomas have different antigenicity, which may
account for the conspicuous absence of inflammation within the tumor.

Content Type Journal ArticleCategory Case ReportDOI 10.1007/BF02921350Authors
Meora Feinmesser, University of Toronto Department of Pathology, St. Michael’s Hospital 30 Bond Street M5B 1W8 Toronto Ontario CanadaDavid Murray, University of Toronto Department of Pathology, St. Michael’s Hospital 30 Bond Street M5B 1W8 Toronto Ontario CanadaNicholas Colapinto, University of Toronto Department of Surgery, St. Michael’s Hospital Toronto Ontario CanadaSylvia L. Asa, University of Toronto Department of Pathology, St. Michael’s Hospital 30 Bond Street M5B 1W8 Toronto Ontario Canada

Journal Endocrine PathologyOnline ISSN 1559-0097Print ISSN 1046-3976

Journal Volume Volume 3

Journal Issue Volume 3, Number 2 / June, 1992 (Source: Endocrine Pathology)  MedWorm Sponsored Message: Find out how you can get your message across here by sponsoring this MedWorm news feed.