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Hashimoto's thyroiditis in down's syndrome: clinical presentation and evolution

Horm Res 2008;70:278-284 (DOI:10.1159/000157874) (Source: Hormone Research)  MedWorm Sponsored Message: Find out how you can get your message across here by sponsoring this MedWorm news feed.

Serum thyroid hormone levels may not accurately reflect thyroid tissue levels and cardiac function in mild hypothyroidism

The link between thyroid dysfunction and cardiovascular diseases has been recognized for more than 100 years. Although overt hypothyroidism leads to impaired cardiac function and possibly heart failure, the cardiovascular consequences of borderline low thyroid function are not clear. Establishment of a suitable animal model would be helpful. In this study, we characterized a rat model to study the relationship between cardiovascular function and graded levels of thyroid activity.

Complications of total thyroidectomy performed by surgical residents versus specialist surgeons

Abstract
Purpose  Surgeon inexperience has been defined as a significant predictor of deleterious outcome in thyroid surgery; however, the safety
of training programs in which residents are the primary surgeons is controversial. The objective of this prospective study
was to compare the complication rates of total thyroidectomy (TT) performed by residents with those of TT performed by specialist
surgeons in similar patient groups.

[hereditary thyroid cancer.]

[Hereditary thyroid cancer.]
Chirurg. 2008 Sep 27;
Authors: Dralle H, Machens A, Lorenz K

Radioiodine treatment for pediatric graves' disease.

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Radioiodine treatment for pediatric Graves' disease.
Cochrane Database Syst Rev. 2008;(3):CD006294

Change of serum anti-thyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin negative pat

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Change of Serum Anti-Thyroglobulin Antibody Levels Is Useful for Prediction of Clinical Recurrence in Thyroglobulin Negative Patients with Differentiated Thyroid Carcinoma.
J Clin Endocrinol Metab. 2008 Sep 23;
Authors: Kim WG, Yoon JH, Kim WB, Kim TY, Kim EY, Kim JM, Ryu JS, Gong G, Hong SJ, Shong YK

Neuromonitoring and video-assisted thyroidectomy: a prospective, randomized case-control evaluation

Abstract
Introduction  This study evaluates the role of intraoperative neuromonitoring (IONM) in video-assisted thyroidectomy (VAT) with emphasis
given to the identification of recurrent laryngeal nerve (RLN) and external branch of superior laryngeal nerve (EBSLN).

Methods  The study was based on a prospectively randomized series comprising 72 standard VAT gasless approaches. In the control group
(N = 36), the laryngeal nerves were identified by 30° 5-mm endoscope magnification solely. The standard technique of the IONM

P53 codon 72 proline/arginine polymorphism and autoimmune thyroid diseases

p53 protein participates in the processes of apoptosis, which is involved in a number of immunological reactions. In order to test whether the p53 gene could be used as a genetic marker for the prediction of the development of autoimmune thyroid diseases (AITD), we screened, by using polymerase chain reaction (PCR) analysis, for the C (CC_C)/G (CG_C) polymorphism at the p53 codon 72 (Pro 72/Arg 72) to determine the genotypes of 107 Hashimoto's thyroiditis (HT) and 90 Graves' disease (GD) patients, and 105 normal controls.

P53 codon 72 proline/arginine polymorphism and autoimmune thyroid diseases.

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p53 codon 72 proline/arginine polymorphism and autoimmune thyroid diseases.
J Clin Lab Anal. 2008 Sep 19;22(5):321-326

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