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 Thursday February 09, 2012       10:24 pm
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Neuromonitoring and video-assisted thyroidectomy: a prospective, randomized case-control evaluation

Abstract
Introduction  This study evaluates the role of intraoperative neuromonitoring (IONM) in video-assisted thyroidectomy (VAT) with emphasis
given to the identification of recurrent laryngeal nerve (RLN) and external branch of superior laryngeal nerve (EBSLN).

Methods  The study was based on a prospectively randomized series comprising 72 standard VAT gasless approaches. In the control group
(N = 36), the laryngeal nerves were identified by 30° 5-mm endoscope magnification solely. The standard technique of the IONM

P53 codon 72 proline/arginine polymorphism and autoimmune thyroid diseases

p53 protein participates in the processes of apoptosis, which is involved in a number of immunological reactions. In order to test whether the p53 gene could be used as a genetic marker for the prediction of the development of autoimmune thyroid diseases (AITD), we screened, by using polymerase chain reaction (PCR) analysis, for the C (CC_C)/G (CG_C) polymorphism at the p53 codon 72 (Pro 72/Arg 72) to determine the genotypes of 107 Hashimoto's thyroiditis (HT) and 90 Graves' disease (GD) patients, and 105 normal controls.

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