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Thyroidectomies from patients with history of therapeutic radiation during childhood and adolescence have a unique mutational profile

Modern Pathology advance online publication, June 27, 2008. doi:10.1038/modpathol.2008.122

Authors: Adel Assaad, Laura Voeghtly
& Jennifer L Hunt (Source: Modern Pathology AOP)  MedWorm Sponsored Message: Find out how you can get your message across here by sponsoring this MedWorm news feed.

Abstract  A 44-year-old woman came to medical attention with right thyroid lobe enlargement and weight loss. Thyroid scan and ultrasound
demonstrated a nodule in the right thyroid lobe; a right hemithyroidectomy was performed. Histologic examination documented
granulomatous and lymphocytic thyroiditis associated with a follicular adenoma. No inflammation was apparent within the adenoma.
The parallels between granulomatous thyroiditis and lymphocytic thyroiditis, including presumed viral initiation and deranged

Abstract
Background  In surgery for primary hyperparathyroidism, preoperative localization together with intraoperative parathyroid hormone assay
is important when minimal invasive operations of the parathyroid glands are intended. In cases of reoperation, correct localization
of the abnormal parathyroid glands is extremely instrumental. Computed tomography (CT)–99mTc-sestamibi (MIBI)–single photon emission computed tomography (SPECT) image fusion allows for a virtual exploration of the

Background: Autoimmune diseases have been implicated in the genesis of MALT lymphoma of various localizations. The development of thyroidal MALT lymphoma has been described as an adverse event in patients suffering from long-standing chronic autoimmune thyroiditis (CAT, Hashimoto's thyroiditis). The percentage and possible association between CAT and extrathyroidal MALT lymphoma, however, have not been assessed so far.

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Patterns of relapse following radiotherapy for differentiated thyroid cancer: Implication for target volume delineation.

Page: 231DOI: 10.1097/SLE.0b013e31816907d0Authors: Bae, Ja Seong MD *; Cho, Young Up MD +; Sung, Gi Young MD *; Oh, Se Jeong MD *; Jung, Eun Jung MD ++; Lee, Jae Bok MD [S]; Kim, Tae Hyun MD [//]; Nam, Kee-Hyun MD [P]; Chung, Woong Youn MD [P]; Yoon, Jung Han MD [sharp]; Kim, Lee Su MD **; Park, Yong Lai MD ++; Kim, Jung Han MD ++; Moon, Byung In MD ++++; Lee, Jong Riul MD [S][S]; Lee, Byoung Un MD [//][//]; Kim, Jee-Soo MD [P][P]; Yoon, Jong Ho MD **; Kim, Je Ryong MD [sharp][sharp]; Soh, Euy Young MD ***; Youn, Yeo Kyu MD +++; Park, Cheong Soo MD [P]; Kim, Jeong Soo MD,

Abstract
Background  Postoperative hypocalcemia is the most common complication after thyroidectomy. New surgical devices have been propose to
achieve vessel sealing and hemostasis. However, the risk of parathyroid glands damage has not been fully elucidated. This
prospective study was designed to evaluate the severity of hypocalcemia after total thyroidectomy by using two different sealing
devices.

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Post-operative PTH measurement facilitates day 1 discharge after total thyroidectomy.

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Minireview: Highly sensitive thyroglobulin measurements in differentiated thyroid carcinoma management.
Clin Chem Lab Med. 2008 Jun 20;
Authors: Giovanella L

A 14-year-old female presented with intermittent abdominal pain, deepening of voice and amenorrhoea for 4 months. Twelve months earlier she had had a thyroidectomy because of familial multinodular goiter and had, subsequently, received substitution with L-thyroxine. At the time of admission, a high serum testosterone level was detected. The dexamethasone suppression test confirmed the hormonal autonomy and magnetic resonance imaging (MRI) visualized a solid tumor within the left ovary. The pathological diagnosis after left salpingo-oophorectomy was Sertoli-Leydig cell tumor.