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A before and after study in thyroidectomy patients found that supplementation with levothyroxine (LT4) alone gave tri-iodothyronine (T3) levels similar to those naturally present pre-operatively.

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Regul Pept. 2008 Feb 19;
Authors: Heymann MF, Riet A, Le Goff B, Battaglia S, Paineau J, Heymann D

(Source: JAMA)

Context  Thyroidal production of triiodothyronine (T3) is absent in athyreotic patients, leading to the suggestion that T3 deficiency may be unavoidable during levothyroxine (LT4) therapy. However, trials evaluating therapy with combined LT4 and T3 have failed to demonstrate any consistent advantage of combination therapy.
Objective  To determine whether T3 levels in patients treated with LT4 therapy were truly lower than in the same patients with native thyroid function.