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 Monday January 05, 2009       10:24 pm
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Clinical significance of p53 protein expression in papillary thyroid carcinoma

Abstract
Background  Although mutations in the p53 suppressor gene in thyroid carcinoma have usually been detected in anaplastic carcinoma, P53 protein expression has been
detected immunohistochemically in papillary thyroid carcinoma (PTC). In the present study, we examined the immunohistochemical
expression of P53 protein in PTC to investigate the relations between its expression and the clinicopathologic features.

Methods  The study was performed on 68 patients in whom thyroidectomy with lymph node dissection had been performed to treat PTC at

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