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Concurrent immune thrombocytopenic purpura and guillain-barre syndrome in a patient with hashimoto's thyroiditis
Tue, 09/19/2006 - 03:00Immune thrombocytopenic purpura (ITP), Guillain-Barre syndrome (GBS), and Hashimoto's thyroiditis (HT) are autoimmune disorders caused by impaired self-tolerance mechanisms triggered by interaction between genetic and environmental factors. ITP is an immune-mediated destruction of platelets resulting in mucocutaneous bleeding, GBS is an ascending motor paralysis caused by an inflammatory demyelination of peripheral nerves, and HT is characterized by autoimmune-mediated destruction of the thyroid gland.
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A differential association of interferon-γ high-producing allele t and low-producing allele a (+874 a/t) with hashimoto's thyroi
Thu, 09/14/2006 - 07:18Scandinavian Journal of Immunology Volume 64, Issue 4, Page 438-443, Oct 2006. (Source: Scandinavian Journal of Immunology)
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